ड्रेस कोड' वादावर LensKart ने मागितली माफी - #lenskart #dresscode #controversy #apology #businessnews #brandcontroversy #publicreaction #marketing #brandimage #LetsUppMarathi #LetsUppNews

Breaking …. #crudeoil #i̇ndianews #irannews #war #breaking

#Iran #USA #War #Update

#Iran’s army chief Amir Hatami says troops “will confront the enemy until the last breath” as concerns persist over a possible return to #war when the #US-Iran ceasefire expires on Wednesday.⁠ .⁠ Hatami pledged to defend the country’s “independence, territorial integrity and security across land, air and sea”.⁠ .⁠ The army, alongside other branches of the armed forces, remains prepared to confront “enemies decisively while advancing military capabilities," he added.⁠ .⁠ 🔴 Follow our LIVE coverage - link in bio.⁠ .⁠ 📸 Iranian Army via apnews

The intellectual and moral collapse of the NY Times as "the paper of record." A play in two acts: Act 1: In 2020, more than 800 reporters, editors, and staff at NY Times revolt and protest the publication of op-ed by Senator Tom Cotton arguing that troops should be deployed, like they were in the 1960s, to quell nationwide riots that summer. The newspaper apologizes to the world for publishing the op-ed and the editor of the op-ed page is forced to resign (James Bennett). Act 2: In 2026, NY Times publishes a massive puff piece *news article* (not op-ed) about "progressive" Hasan Piker, who has called for assassination of a U.S. Senator, says Hamas is "1,000 times better than Israel," says "America deserved 9/11," supports Islamic regime of Iran, and mourns the collapse of the Soviet Union. When elites at the NY Times bemoan the loss of trust and respect for institutions like the media, they should take a long look in the mirror to discover the real reasons for this loss of trust.

Dendritic cells are innate immune cells that regulate the quality, magnitude, and duration of antitumor responses. Conventional type 1 dendritic cells (cDC1s) are crucial in this capacity but are paradoxically rare and functionally impaired in most solid tumors. This is a major barrier to effective immunotherapy. ⁠ ⁠ The molecular underpinnings of cDC1 dysfunction within the tumor microenvironment are poorly understood. In a new Science study, researchers report that mitochondrial fitness is important for cDC1 function. ⁠ ⁠ They also demonstrate the therapeutic rescue of cDC1 function within the tumor microenvironment in mice, which provides a framework for metabolically reprogramming dendritic cells to restore antitumor immunity.⁠ ⁠ Learn more by clicking the link in our bio.⁠ ⁠ GRAPHIC CREDIT: K. HOLOSKI/SCIENCE

Ilhan Omar says there is growing h*te toward Muslims and immigrants in the country 🚨🗣️ Ilhan Omar has drawn attention after speaking about rising hostility faced by certain communities. In a recent statement, she highlighted concerns about increasing h*te directed toward Muslims and immigrants, pointing to a broader social issue that continues to shape national conversations around identity and inclusion. Omar said, “Ilhan Omar said, ‘There’s a lot of hte in this country for Muslims. There’s a lot of severe hte for immigrants.’” Her remarks reflect ongoing debates about discrimination, public rhetoric, and how different communities experience life in the United States amid political and cultural divisions. The comments have sparked mixed reactions, with some supporting her concerns and others challenging her perspective. The discussion underscores a wider debate about social cohesion, public safety, and the role of leadership in addressing tensions affecting diverse communities across the country. #fblifestyle #photography #community #ilhanomar #immigration #socialissues References: BBC News: Debate Over Rising Hate And Discrimination In The United States Reuters: Lawmakers Address Concerns Over Community Safety And Inclusion CNN: Ilhan Omar Speaks On Treatment Of Muslims And Immigrants Fox News: Reactions Follow Omar’s Comments On Social Division

Bacteria are full of diverse molecular tricks. This Science article reports an interesting one that is being misrepresented by news coverage, including the coverage in Science. The study describes an enzyme complex that synthesizes alternating dinucleotide repeat DNA as part of an immune response. Protein templating DNA is a cool observation, even if the sequence is only a repeating dinucleotide. The headline-grabbing takeaway is the mechanism of the Drt3b subunit. While its partner, Drt3a, uses a canonical RNA template (reverse transcription), Drt3b synthesizes the complementary strand in the absence of a nucleic acid template. Instead, it uses specific amino acid residues (a glutamate and an arginine) to stabilize and "select" the incoming dNTPs. It is tempting to view this as a radical shift in our understanding of information transfer, a "protein-templated" genetic sequence. However, we should be cautious with the "paradigm shift" narrative. Why this isn't "rewriting" the Genetic Code: Despite claims in the news coverage, this finding does not represent a new form of hereditary information transfer. This is not a protein "reading" itself to create a complex message; rather, it is a highly specialized structural constraint. The protein is essentially a "stuttering" machine, physically keyed to produce a simple, repetitive sequence. The "information" is hard-coded into the protein's fold to perform a single, specific defensive task, rather than acting as a general-purpose template for diverse genetic messages. The Parallel to tmRNA: This observation is not entirely unprecedented when we look at how bacteria handle biochemical "dead ends." It reminds me of transfer-messenger RNA (tmRNA). In trans-translation, when a ribosome stalls on a broken mRNA, the tmRNA molecule steps in to provide both the tRNA component and a short mRNA "tag" to rescue the ribosome: - The "Non-Standard" Template: Much like tmRNA provides an external sequence to fix a stalled process, the DRT3 ncRNA and the Drt3b protein provide "internal" instructions to create DNA where no genomic template exists. - Specialized Rescue: Both mechanisms are niche "emergency" responses, one for proteostasis (tmRNA) and one for viral defense (DRT3). In the end, this discovery doesn't replace our understanding of the genetic code; it expands the "toolbox" of how cells can synthesize polynucleotides when the standard rules don't apply. It is a beautiful reminder that in the microbial world, if a chemical shortcut is possible, evolution has likely found it.